Inhibition of NF-kB activation attenuated irradiated MCF-7-induced tube network formation.

Then, we examined the communication of angiogenic signals from irradiated MCF-7 cells to vascular endothelial cells.

We also observed corresponding expression of VEGFR2 and FGFR1 in non-irradiated endothelial cells that were co-cultured with irradiated MCF-7 cells.