Anosmia has been noticed in leukoderma and allied disturbances of pigmentation.

Figure 293 represents a family of three children, all the subjects of leukoderma.

Ogle mentions a negro boy in Kentucky whose sense of smell decreased as the leukoderma extended.

Wood calls attention to the wave-like course of leukoderma, receding on one side, increasing on the other.

It has been ascribed to syphilis; but syphilitic leukoderma is generally the result of cicatrices following syphilitic ulceration.

Leukoderma is as common in housemaids as in field-laborers, and is in no way attributable to exposure of sun or wind.

Leukoderma is a pathologic process, the result of which is a deficiency in the normal pigmentation of the skin, and possibly its appendages.