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1
In contrast, MDCK-D1 cells contained a single population of
low
affinity
sites.
2
The
low
affinity
sites for agonists are in the micromolar range.
3
Protein-glycan interactions are typically
low
affinity
,
requiring multivalent interactions to achieve a biological effect.
4
In addition, we identified many FimH variants that appear locked in the
low
affinity
state.
5
However, levels of 20-HETE, which is known to bind the peptide with
low
affinity
,
were unchanged.
6
They can be considered as new dendrotoxins, albeit with fairly
low
affinity
as compared to alpha-DTX.
7
Because some of these interactions are of
low
affinity
,
we suspect the additional linkages also exist.
8
However, the interactions between individual carbohydrates and proteins are often of
low
affinity
and difficult to study.
9
Here, we demonstrate
low
affinity
of CRRETAWAC for platelets and platelet integrins, thus providing it with EC-selectivity.
10
In GCs, high-affinity B cells accumulated fewer V(H) somatic mutations than
low
affinity
B cells.
11
Isolated beta had very
low
affinity
for nucleotide as compared to the first catalytic site on F1.
12
In contrast to traditional vectors, rAAV9 showed high affinity for myocardium but
low
affinity
for liver and other organs.
13
The
low
affinity
neurotrophin receptor (p75NTR) has been shown to mediate the apoptosis signaling to neural cells.
14
Most reported endogenous PPARgamma ligands are intermediates of lipid metabolism and oxidation that bind PPARgamma with very
low
affinity
.
15
FPR2 is a
low
affinity
receptor for formyl peptides and it is considered the most promiscuous member of this family.
16
By varying the ADP or ATP concentration in flow chamber, we determined that OxPhos has a
low
affinity
in cardiomyocytes.
low
affinity
low