1
Consequently, ENaC is a major effector impacting systemic blood volume and pressure.
2
YAP1 is a major effector of the Hippo pathway and a well-established oncogene.
3
Perforin has been identified as the major effector molecule acting against many fungal pathogens.
4
Eosinophils are major effector cells in allergic tissue reactions.
5
Of the two, Cin8p is the major effector and its activity requires a functional motor domain.
6
Our analysis identified a model where kinesin-5 … Of the two, Cin8p is the major effector and its activity requires a functional motor domain.
7
The cytokine interleukin 13 (IL-13) is a major effector molecule for T-helper type 2 inflammation and is pathogenic in allergic diseases such as asthma.
8
The major effectors are antibody to the E2 surface glycoprotein produced by B cells, and interferon-gamma produced by T cells.
9
Accumulating evidence indicates that hepatic stellate cells (HSCs) are the central mediators and major effectors in the development of hepatic fibrosis.
10
For these reasons, the major effectors cells of the innate immune system, macrophages, have been a particular focus in international genome and transcriptome consortia.
11
Objective: Invasive synovial fibroblasts are suggested to be the major effectors of cartilage and bone destruction, and this aggressive phenotype can lead to irreversible damage.