Meanings of major effectors in English

The major effectors are antibody to the E2 surface glycoprotein produced by B cells, and interferon-gamma produced by T cells.

Accumulating evidence indicates that hepatic stellate cells (HSCs) are the central mediators and major effectors in the development of hepatic fibrosis.

For these reasons, the major effectors cells of the innate immune system, macrophages, have been a particular focus in international genome and transcriptome consortia.

Objective: Invasive synovial fibroblasts are suggested to be the major effectors of cartilage and bone destruction, and this aggressive phenotype can lead to irreversible damage.