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Meanings of major obstacle in English

We have no meanings for "major obstacle" in our records yet.
Usage of major obstacle in English
1
However, efficient delivery into tumor cells remains a major obstacle for treatment.
Pubmed
2
This, of course, is a major obstacle to tracing one's family roots.
The Irish Times
3
The major obstacle to implementing UGRA in clinical practice was time pressure.
Pubmed
4
It is a major obstacle for Gazprom, said gas analyst Mikhail Korchemkin.
Reuters
5
Methicillin resistance creates a major obstacle for treatment of Staphylococcus aureus infections.
Pubmed
6
Ike briefly explained that the Leine River was not a major obstacle.
Red inferno: 1945
7
The island's division is a major obstacle to Turkey's European Union aspirations
The Irish Times
8
Purpose: Resistance to chemotherapy-induced apoptosis represents a major obstacle to cancer control.
Pubmed
9
Conclusions: This study highlighted financial difficulty as the major obstacle to obtaining treatment.
Pubmed
10
However, the planets suggest that there is one major obstacle to remove first!
The South African
11
Background: Rejection of allografts has always been the major obstacle to transplantation success.
Pubmed
12
Beyond the lack of economic resources, Marci faced another major obstacle.
Rock and Ice Magazine
13
This creates a major obstacle to the Tories' chances of winning a majority.
The Guardian
14
This is a major obstacle to achieving universal access to ART.
Pubmed
15
This is a major obstacle for the design and evaluation of preventive vaccines.
Pubmed
16
A major obstacle to application is that cellular membranes are impermeable to trehalose.
Pubmed
This collocation consists of:
Major obstacle through the time
Major obstacle across language varieties
United States of America
Common
Ireland
Common
United Kingdom
Rare