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Goodfellow's theory was comfortingly simple, but suffered from a major shortcoming.
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The other major shortcoming of Punakea is that its bookmark support is limited to Safari.
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A major shortcoming to plasmid-based genetic tools is the necessity of using antibiotics to ensure plasmid maintenance.
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Nagios's major shortcoming is its daunting complexity.
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Implications for practice: The results suggest a major shortcoming in both preparation for survivorship, multidisciplinary follow-ups, and knowledge.
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The major shortcoming is the assumption of the inevitability of reprisals and the capacity to take punitive action.
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However, a major shortcoming with these systems has been the inability to fabricate structures with controlled micrometer-scale features on a biologically relevant length scale.
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On Monday, French Economy Minister Christine Lagarde said it highlighted major shortcomings at SocGen.
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Ehrlich said that there were other possible assessments available, but that these had major shortcomings.
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Recently, we have optimized a protocol to overcome the major shortcomings of a typical bacterial expression system.
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But we identified major shortcomings, too.
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Tracing is the biggest challenge and experts have identified major shortcomings in the methods being used by the government.
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An independent review has identified major shortcomings in one of the main services for school children who are struggling to read.
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It took an unannounced inspection by the newly appointed Health Information and Quality Authority (Hiqa) to officially identify major shortcomings.
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It found inadequate planning, poor training and unclear policies among a long list of " major shortcomings" in the department's response.
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Lead author Dr Zaheer-Ud-Din Babar said the study found major shortcomings in pricing policy, and he supported calls for greater transparency of funded drugs.