Meanings of marked loss in English

PMG is characterized by a marked loss of deep cortical fissures.

These data indicate that most DAX1 missense mutations associated with classic AHC exhibit marked loss of function.

But readings by sector showed a more marked loss of momentum in critical areas at the start of the third quarter.

If Dr. Leonard had survived without any marked loss a dozen years of venturing, he might be said to have succeeded.

Frameshift or point mutations resulting in marked loss of coding information are found in patients who develop antibodies to administered factor IX.

Results: 55% of the carcinomas showed a marked loss or absence of FHIT expression compared with their matched normal mucosa.

Results: We identified robust cachexia in the HCC mouse model as evidenced by a marked loss of visceral fat and lean mass.

There was no difference in beta-NGF content in any region examined in AD compared with normal values despite the marked loss of cortical cholinergic function.

Children with AD and wheeze have a marked loss in lung function, suggesting a distinct phenotype rather than a progressive development from AD to asthma.

One female subject with FPLD2 followed from age 6 to 16 years revealed marked loss of extremity fat much before thelarche.