Results: Distinct pathways mediate apoptosis in response to death receptor stimulation and ionizing radiation although an overlapping set of molecules is involved.

However, the mechanism of mitochondria- mediated apoptosis in aged hearts remains poorly understood.

This suggested that endogenous Bcl-XL could protect cancer cells from p53- mediated apoptosis.

IRE1a inhibition ER stress- mediated apoptosis lies in the process of chondrocyte differentiation.

Furthermore, siXBP1S can enhance ER stress- mediated apoptosis and main matrix degradation in osteoarthritis.

ROS- mediated apoptosis may be further aggravated by an inadequate cytoprotective response against ROS.

In this study, we investigated the sensitivity of CIK cells to Fas- mediated apoptosis.

RICK, a novel protein kinase that regulates CD95- mediated apoptosis was identified and characterized.

The Rsk-induced phosphorylation of BAD at serine 112 suppressed BAD- mediated apoptosis in neurons.

Here, we report that cells expressing Wnt-1 were resistant to cancer therapy- mediated apoptosis.

COX inhibitor- mediated apoptosis is associated with the induction of TAp73beta and its target genes.

A proteomic approach was used to assess the protein expression profile associated with STGC3- mediated apoptosis.

Background: Eosinophils and lymphocytes are pathogenically important in allergic inflammation and sensitive to Fas- mediated apoptosis.

The underlying mechanisms by which tumor cells are resistant to CTL- mediated apoptosis are not clear.

This event desensitizes FasL- mediated apoptosis by inhibiting extracellular signal regulated kinase activity and up-regulating NF-kappaB.

Also, TUNEL staining of CHOP-positive renal tubular cells suggests CHOP mediates apoptosis in these cells.