Meanings of mediate signaling in English

Janus kinases (JAK) are enzymes that mediate signaling of several important drivers of inflammatory diseases and certain bone marrow disorders.

Nucleotides released from activated or dying cells at sites of inflammation can mediate signaling through purinergic receptor family II, resulting in CD62L shedding.

Hsp90 interacts with proteins that mediate signaling pathways involved in the regulation of essential processes such as proliferation, cell cycle control, angiogenesis and apoptosis.

NF-kB1- mediated signaling regulates the development of gastric mucosal pathology following TAM administration.

Anesthetics are known to modulate hemodynamics, receptor- mediated signaling cascades, and outcome parameters.

Functional cross-talk between estrogen-signaling and growth factor- mediated signaling pathways has been reported.

Gene Ontology analysis identified RabGTPase mediated signaling as the most represented pathway.

However, the regulatory mechanisms underlying STING- mediated signaling are not fully understood.

Phosphoproteomics enables interrogation of kinase mediated signaling pathways in biological systems.

PAC1- mediated signaling has been implicated in neuronal differentiation and synaptic plasticity.

In cholestasis, bile acids induce hepatocyte apoptosis by primarily activating death receptor- mediated signaling.

Therefore, miR-155- mediated signaling pathways became a potential target for the molecular treatment of cancer.

In vitro experiments confirmed reconstitution of IL-10R- mediated signaling in all patients who received the transplant.

JAGN1 participates in the secretory pathway and is required for granulocyte colony-stimulating factor receptor- mediated signaling.

We demonstrate that histamine- mediated signaling contributes to malaria pathogenesis.

Recent studies reveal that internalization and trafficking of Trks play a critical role in neurotrophin- mediated signaling.