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1 It interacts with both mineralocorticoids and glucocorticoids to mediate transcription of target genes.
2 We propose that such binding may block RNA polymerase II- mediated transcription .
3 Transient transfection experiments showed that PAK6 specifically repressed AR- mediated transcription .
4 Mechanical force and Wnt signaling activate β-catenin- mediated transcription to promote proliferation and tissue expansion.
5 This modification was not required for DNA binding, but may be important in STAT- mediated transcription .
6 Our findings demonstrate that Wnt3a plays an important role in androgen- mediated transcription and cell growth.
7 These results suggest an interdependent relationship between the JNK and SMAD pathways in TGF-beta- mediated transcription .
8 Here we show that these complexes have selectivity in mediating transcription of different interferon-responsive genes.
9 Rapidly growing cancer cells are characterized by increased Pol I- mediated transcription and, consequently, nucleolar hypertrophy.
10 These results indicate that type I myotubes are dependent upon Egr3- mediated transcription for proper spindle development.
11 Transfection of either wild-type or a constitutively active mutant of the IGF-I receptor augments AR- mediated transcription .
12 BRF1 is a rate-limiting factor for RNA Polymerase III- mediated transcription and is elevated in numerous cancers.
13 In this study, we performed several experiments to test whether beta-catenin is involved in IGF-I-induced AR- mediated transcription .
14 Using gene transfer studies it was shown that these sequences are necessary and sufficient for ER- mediated transcription .
15 The mechanism of TAZ- mediated transcription is unclear.
16 Co-expression of PTEN and LZTS2 in prostate cancer cells shows stronger repressive effect on ß-catenin mediated transcription .
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