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Distinct E GSH were observed in the cytoplasm and the mitochondrialmatrix.
2
Pos5p is the only known NADH kinase in the mitochondrialmatrix.
3
Pyruvate is a major gluconeogenic substrate and requires import into the mitochondrialmatrix for channeling into gluconeogenesis.
4
Recent studies have demonstrated that Abeta progressively accumulates within mitochondrialmatrix, providing a direct link to mitochondrial toxicity.
5
It is known that a signal peptide is required for the import of a protein into mitochondrialmatrix.
6
Rhod 2 does not display this shortcoming, but like other indicators, it also loads into the mitochondrialmatrix.
7
Perturbation of the protein-folding environment in the mitochondrialmatrix selectively upregulates the expression of nuclear genes encoding mitochondrial chaperones.
8
These complexes are imported into the mitochondrialmatrix through the outer and inner membrane import channels of isolated mitochondria.
9
The intercristal space was occupied by a mitochondrialmatrix which contained electron-dense matrix granules, mitochondrial DNA, and ribonucleoprotein granules.
10
Here, we have tested whether mitochondrialmatrix pH controls oxidative phosphorylation and metabolism-secretion coupling in the rat β-cell line INS-1E.
11
Acidification of the mitochondrialmatrix pH by nigericin blunted nutrient-dependent respiratory and ATP responses (continuously monitored in intact cells).
12
Besides CoQ, also oxygen may be an electron acceptor from the enzyme, with generation of superoxide radical in the mitochondrialmatrix.
13
The association of mitochondrialmatrix AAA+ proteases with cancer and their potential for therapeutic modulation therefore warrant further consideration.
14
Separated fragments fuse within a few minutes to the large part, resulting in a rapid intermixing of the entire mitochondrialmatrix compartment.
15
Tight control of protein homeostasis is required for the maintenance of mitochondrial function, and the mitochondrialmatrix houses several coordinated protein quality control systems.
16
Approximately 60% of the high-speed GDH activity was particulate (associated with membrane) and the remaining was soluble (probably of mitochondrialmatrix origin).