The agreements have been modified multiple times in the decades since.

Measurements and main results: Non-neurologic organ dysfunction was measured by the maximum modified multiple organ dysfunction score.

A modified multiple baseline, across-participants design was used to evaluate the effects of memantine on the severity of naloxone-precipitated opioid withdrawal.

The law, which has been modified multiple times since then, was intended to hold captains, engineers and pilots responsible for deaths attributable to their conduct.