Using sequential analyses, we then compared the risk of intussusception among children receiving monovalentrotavirus vaccine with historical background rates.
2
We further compared the risk after monovalentrotavirus vaccination with the risk in a concurrent cohort of infants who received the pentavalent rotavirus vaccine.
3
We reviewed medical records and visits for intussusception within 7 days after monovalentrotavirus vaccination from April 2008 through March 2013.
4
The group receiving only the monovalentrotavirus vaccine received 2 doses of vaccine and the other 4 groups received 3 doses of vaccine.
5
The attributable risk of intussusception after the administration of two doses of monovalentrotavirus vaccine was estimated to be 5.3 per 100,000 infants vaccinated.