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Multiple system atrophy (MSA) is a neurodegenerative disorder characterized by autonomic failure (cardiovascular and/or urinary), parkinsonism, cerebellar impairment and corticospinal signs with a median survival of 6-9 years.
All the patients with multiplesystematrophy had hyperreflexia with synergy.
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A diagnosis of multiplesystematrophy was made, supported by MRI findings and evidence of autonomic dysfunction.
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Urodynamic findings may be abnormal before patients with multiplesystematrophy reach an advanced stage of the disease.
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Degenerative processes of disease-specific tracts were clearly identified as illustrated in cases of multiplesystematrophy and Joseph-Machado disease.
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Objective: To explore the prognostic factors for inability to walk independently in patients with multiplesystematrophy (MSA).
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We report a 57-year-old woman with multiplesystematrophy (MSA) of 15-month duration.
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Conclusions: Urodynamic evaluation and sphincter EMG are both useful tests in the differential diagnosis between Parkinson's disease and multiplesystematrophy.
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Increased age at death was observed in the minimal pathology group, amyotrophic lateral sclerosis, and multiplesystematrophy cases with co-pathologies.
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Recordings of EMGs from perineal muscles become abnormal as the disease progresses in multiplesystematrophy but not in Parkinson's disease.
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Our case presented with depression and RBD that preceded parkinsonism, and dysautonomia that led to an initial diagnosis of multiplesystematrophy.
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A 60-year old man with a 10-year history of multiplesystematrophy (MSA) was found in respiratory arrest.
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Furthermore, SV2C expression is dramatically altered in postmortem brain tissue from PD cases but not in Alzheimer disease, progressive supranuclear palsy, or multiplesystematrophy.
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Methods: Sixty two patients (30 with Parkinson's disease and 32 with multiplesystematrophy) underwent a complete urodynamic evaluation and neurophysiological testing.
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A postmortem examination performed after she was found dead in … We report a 57-year-old woman with multiplesystematrophy (MSA) of 15-month duration.
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Background: Multiplesystematrophy (MSA) is a rapidly progressive neurodegenerative disorder which causes early sustained disability and quality of life impairment.
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Multiplesystematrophy (MSA) is a sporadic and rapidly progressive neurodegenerative disorder that presents with autonomic failure in combination with parkinsonism or cerebellar ataxia.