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The mammalian mdr gene family comprises a small number of closely related genes.
2
Expression levels of each mdr gene are dramatically different in various mouse tissues.
3
Each of the mdr genes has a specific RNA transcript pattern.
4
Tet could downregulate the level of mdr-1 gene and decrease the expression of P-gp.
5
In addition, a number of strategies aimed at reversing the mdr phenotype are under study.
1
The xenograft leukemia model with stable multipledrugresistance in nude mice was established.
2
These results suggest that doxorubicin resistance is multifactorial and alternative mechanisms of multipledrugresistance remain to be determined.
3
These data cumulatively suggest that the taccalonolides have advantages over the taxanes in their ability to circumvent multipledrugresistance mechanisms.
4
The multipledrugresistance protein 1 (MRP1 or ABCC1) transports anticancer drugs and normal cell metabolites.
5
Chemotherapy and targeted therapy can significantly improve survival rates in cancer, but multipledrugresistance (MDR) limits the efficacy of these approaches.
1
Possible contributors include multidrugresistance, extensive virulence gene content, and ongoing transmission.
2
The study showed that elevated hsps were not associated with multidrugresistance.
3
These results hold significant implications for the study of multidrugresistance in vivo.
4
Silymarin complex was previously described as an antioxidant with multidrugresistance modulation activity.
5
We are concerned about the multidrugresistance of A. baumannii in this study.
1
Cases of multi-drugresistance were recorded in the present study and require further consideration.
2
The development of non-P-glycoprotein-mediated multi-drugresistance is a frequent event among lung-cancer cell lines.
3
Background: Efflux pumps of the Resistance-Nodulation-cell Division superfamily confer multi-drugresistance to Gram-negative bacteria.
4
In summary, there may be a significant contribution of transcriptional activation to multi-drugresistance.
5
High Glo1 expression is a cause of multi-drugresistance.
Usage of multiresistance in English
1
Although more subjective, there is also no consensus regarding the definition of multiresistance.