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Thus, the enzyme has potential as a component of a multivalentvaccine against schistosomiasis.
2
No single viral variant can induce sufficiently broad immunity, and incorporating all known naturally circulating variants into one multivalentvaccine is not feasible.
3
These observations support the feasibility of a multivalentvaccine against shigellosis and ETEC diarrhea consisting of multiple Shigella live vectors expressing relevant ETEC antigens.
4
These results have implications for the design of multivalentvaccines.
5
Furthermore, to reduce the burden of vaccination, the development of multivalentvaccines is highly desirable.
6
Our study suggests that multivalentvaccines may be more suitable in this setting, especially for HIV-infected individuals.
7
The use of such multivalentvaccines did not show overt immune interference in comparison with monovalent vaccines.
8
Collectively, our results support previous reports about the potential benefit of EV-A71 vaccine but highlight the necessity of multivalentvaccines to control HFMD.