Meanings of negative modulator in English

Collectively, our results identify NLRC5 as a negative modulator of inflammatory pathways.

It was implied that naturally produced sgammac is a negative modulator of gammac-dependent cytokines.

We found that dopamine functioned as a significant negative modulator of glucose-stimulated insulin secretion.

It functions as a negative modulator of the Wnt pathway in LGR5-positive stem cells.

These results also challenge the accepted view that phosphorylation is a universal negative modulator of G protein-coupled receptors.

Our data demonstrates that lynx1 acts as a negative modulator of nicotinic signaling in normal and neoplastic lung.

Myostatin is an important negative modulator of muscle growth during myogenesis, and myostatin inhibitors are attractive drug targets.

Furthermore, functional analyses showed that miR-326 acts as a negative modulator for Shh signaling by directly targeting Smo and Gli2.

These data implicate CD73 acting through adenosine generation and its stimulation of the A2AR as a critical negative modulator of lymphocyte recruitment into airway allografts.

Many factors have been implicated in signal-induced actin polymerization, but the essential nature of the potential negative modulators are still poorly understood.