1
Recent studies suggest early reversible changes involving inflammation and neoangiogenesis.
2
We have developed a combined magnetic resonance and optical toolkit to study neoangiogenesis in glioma models.
3
In the present study we used MR-UM to investigate tumor infiltration and neoangiogenesis in a translational approach.
4
Furthermore, we assess tumor neoangiogenesis in a mouse glioma model to compare tumor core and tumor border.
5
Vascular endothelial growth factor (VEGF) is a central regulator of neoangiogenesis in inflammatory and neoplastic conditions.
6
UM resolved typical features of neoangiogenesis and tumor cell invasion with a spatial resolution of ~5 µm.
7
MR-UM resolves tumor infiltration and neoangiogenesis longitudinally based on the expression of fluorescent proteins, intravital dyes or endogenous contrasts.
8
Conditional ablation of COUP-TFII in the tumor microenvironment severely compromised neoangiogenesis and lymphangiogenesis during pancreatic tumor progression and metastasis.
9
Conclusions: The chick chorioallantoic wound model allows the identification of gene signatures and pathways involved in GT formation and neoangiogenesis.
10
Consistent with this focus, recent clinical trials suggest that blockade of VEGF may impede cancer progression, presumably by preventing neoangiogenesis.
11
Therefore, we demonstrate that uPAR changes the biological characteristics of RA-FLSs, and affects neoangiogenesis of synovial tissues in patients with RA.
12
Capillary loop diameter and length, capillary distribution pattern and presence of neoangiogenesis were found to be significantly increased in postburn scars compared with controls.
13
Neoangiogenesis and migration are requisites to metastasis promotion.
14
Recent studies suggest early reversible changes involving inflammation and neoangiogenesis.
15
We have developed a combined magnetic resonance and optical toolkit to study neoangiogenesis in glioma models.
16
In the present study we used MR-UM to investigate tumor infiltration and neoangiogenesis in a translational approach.