Meanings of notoriously challenging in English

The delivery of therapies to the cochlea is notoriously challenging.

The cultivation and maintenance of naïve PSCs have been notoriously challenging, requiring the use of complex cytokine cocktails.

Marina Piccinini has arranged -and published -Paganini's 24 notoriously challenging solo violin caprices for solo flute.

Auckland Medical Officer of Health William Rainger said the 15-29 group was notoriously challenging to reach.

The notoriously challenging course at the foot of the Dublin Mountains has produced many fine women golfers and teams over the years.

That could prove tricky as deft management of a notoriously challenging Congress will be crucial to ensure passage of her flagship reforms.

Others, of course, see it differently - but no one debates the fact that he kept the lid on a notoriously challenging portfolio.

Many former classics students may "shudder" as they recall "their fear and exertion, their anger and frustration" while learning the notoriously challenging language.