1
NuMA is a spindle protein whose disruption results in nuclear fragmentation.
2
Evidence of apoptosis was determined by TUNEL assay and visualization of nuclear fragmentation by DAPI staining.
3
Caspase cleavage of vimentin disrupts its cytoplasmic network of intermediate filaments and coincides temporally with nuclear fragmentation.
4
Both the trypan blue exclusion assay for cell death and nuclear fragmentation assay for apoptosis were used.
5
In all cell lines examined, fenretinide also induced morphological changes consistent with apoptosis, including cellular shrinkage, chromatin condensation, and nuclear fragmentation.
6
Apoptosis was also evident from the flow cytometric studies of drug-treated HCT-116 cells as well as from the appearance of nuclear fragmentation.
7
Exposure of DU145 cells to NaBu for 24 h caused a strong apoptotic effect with 26% nuclear fragmentation and condensation.
8
A high percentage of HL-60 cells treated with 3-AT exhibited membrane blebbing, pyknosis, and nuclear fragmentation, which was not observed among other 3-AT-treated cell lines.
9
Nuclear fragmentation was also evident.