The small difference in oestradiolconcentration could be aetiologically important, but larger prospective studies are needed.
2
Women who subsequently developed breast cancer had a 29% higher geometric mean oestradiolconcentration than control women (P = 0.004).
3
Serum testosterone and oestradiolconcentrations in ACTH-infused rats remained below levels of detection.
4
Aromatase inhibitors inhibit the conversion of testosterone to oestrogens and could reduce serum oestradiolconcentrations.
5
Women in populations with low breast cancer rates have low serum oestradiolconcentrations both before and after the menopause.
6
These data provide evidence that serum oestradiolconcentrations in post-menopausal women may have a substantial effect on breast cancer risk.
7
This demonstration of reduced proliferative activity indicates that the pharmacological effectiveness of the treatment was maintained despite increased plasma oestradiolconcentrations.