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1 The system determines the presence of powerful toxins, okadaic acid and azaspiracid.
2 The serologic activities of structurally related okadaic acid derivatives have been determined.
3 However, cryptoporic acid D slightly enhanced tumor promotion rather than inhibition of okadaic acid.
4 The biochemical and tumor-promoting activities of calyculin A were studied with those of okadaic acid.
5 These two compounds provided differential effects on tumor promotion of okadaic acid on mouse skin.
6 Application of okadaic acid caused vesicle mobility in both pools to increase to the same level.
7 The results suggest a new pathway of tumor promotion mediated through the okadaic acid receptor(s).
8 Calyculin A is the first tumor promoter to be screened by the okadaic acid receptor binding test.
9 Canventol, a synthetic compound, is a new inhibitor of tumor promotion on mouse skin by okadaic acid.
10 These changes were compared to changes in the phosphoproteome that were induced by pervanadate or okadaic acid exposure.
11 Intra-VH infusion of PP2A inhibitor okadaic acid blocked the anti-aggressive effects of MK-801.
12 Dephosphorylation of a limited number of proteins was shown to be associated with apoptosis and okadaic acid prevented these dephosphorylations.
13 The F- and G-rings of okadaic acid may comprise part of the epitopes recognized by some of the polyclonal antibodies.
14 Structurally unrelated to okadaic acid, calyculin A bound to the okadaic acid receptors in particulate and soluble fractions of mouse skin.
15 The mechanisms of action of the okadaic acid class tumor promoters are discussed with emphasis on the inhibition of protein phosphatase activity.
16 The suitability of a cytotoxicity assay based on the MTT colorimetric method has been evaluated for the detection of okadaic acid in mussels.
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