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Meanings of orthosteric ligands in English
We have no meanings for "orthosteric ligands" in our records yet.
Usage of orthosteric ligands in English
1
Mutations within the orthosteric binding site caused similar reductions in affinity and signaling efficacy for both selective and prototypical orthosteric ligands.
2
However, targeting the largely unexplored and evolutionarily unique allosteric sites has potential for developing more specific drugs with fewer side effects than orthosteric ligands.