Oxidative addition and reductive elimination are two important and related classes of reactions in organometallic chemistry.
1
This causes oxidative addition to become the rate-limiting step in the 1,10-phenanthroline-mediated reaction.
2
The immediate product of the oxidative addition step is found to undergo facile reductive elimination to provide the arylation product.
3
It is suggested that the formation of a T-shaped intermediate could foster the C-H activation via oxidative addition to the metal centre.
4
Because O-coordination of a deprotonated amino alcohol is favored over N-coordination in the oxidative addition transition state, O-arylation is favored with the 1,10-phenanthroline ligand.