Photograph: Allstar People with FTD end up in prison in this way.
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FTD-iPSCs were fated to cortical neurons, the cells most affected in FTD.
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Frontal variant FTD is an unpredictable disease in terms of its biochemistry.
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Methods: Sixty-two patients with a clinical diagnosis of FTD participated in the study.
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Loss of language nevertheless remains the most noticeable symptom of FTD.
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In semanticdementia, there was asymmetrical temporal lobe atrophy, with greater left-sided damage.
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Three groups of 10 subjects were studied: semanticdementia patients, Alzheimer's disease patients, and control subjects.
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Patients with bvFTD and semanticdementia had a strong sucrose preference compared with the other groups.
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She had semanticdementia, a rare disease that slowly and inescapably takes a person's language away.
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This study explored this question by comparing three patients with semanticdementia to 40 normal controls performing different everyday activities.
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Recent research on frontotemporaldementia highlights the potential value of these approaches.
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Results: The frontotemporaldementia subgroup represented approximately half of all FTLD diagnoses.
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Other diseases which may involve tau deposition include frontotemporaldementia and corticobasal degeneration.
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Neuroimaging features were consistent with the diagnosis of frontotemporaldementia.
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The authors conclude that PSEN1 mutations can be associated with clinical features of frontotemporaldementia.
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Hierarchical cluster analysis after exclusion of these 12 genes differentiated 4 of the 6 PD cases from progressive supranuclear palsy and frontotemporaldementiawithparkinsonism.
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This has now changed with the discovery of close to 20 mutations in the tau gene in frontotemporaldementiawithParkinsonism linked to chromosome 17.
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Mary Johnson, age fifty-seven, Frontotemporallobedementia
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Methods: Electronic databases were searched using terms related to frontotemporallobardegeneration and movement disorders.
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Mutations in the gene encoding PGRN give rise to shortage of PGRN and cause familial frontotemporallobardegeneration.
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Summary: This represents the first systematic review and meta-analysis of the occurrence of movement disorder phenomenology in genetic frontotemporallobardegeneration.
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These findings further highlight that plasma PGRN levels may not accurately predict clinical features or response to future frontotemporallobardegeneration therapies.
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Mutations in various RBPs cause several diseases of the central nervous system, including frontotemporallobardegeneration, amyotrophic lateral sclerosis and fragile X syndrome.