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Background: Massively parallel sequencing has recently been used in noninvasive prenatal diagnosis.
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Conclusions: Massively parallel sequencing is a powerful tool for studying posttransplantation chimerism.
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Target enrichment and massively parallel sequencing were performed for each plasma DNA library.
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Massively parallel sequencing of cDNA has enabled deep and efficient probing of transcriptomes.
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Plasma DNA libraries with and without target enrichment were analyzed by massively parallel sequencing.
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Pulldown of expressed sequences from genomic DNA followed by massively parallel sequencing was undertaken.
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In contrast, massively parallel sequencing allows such testing for many genes simultaneously at low cost.
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The advent of massively parallel sequencing will allow the field to expand its capabilities substantially.
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When applied to sequencing the transcriptome, massively parallel sequencing can reveal latent or silent infections.
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Epidermal growth factor receptor (EGFR) mutations were further validated by massive parallel sequencing.
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Background: Massively parallel sequencing of barcoded DNA samples significantly increases screening efficiency for clinically important genes.
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This study demonstrates the cost-effectiveness of investigation using massively parallel sequencing technologies in paediatric muscle disease.
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Massively parallel sequencing (MPS) offers an alternative that can overcome limitations of the CE.
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RNA from 20 tumors was evaluated by massively parallel sequencing to search for potentially oncogenic viruses.
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The DHS map was developed by sequencing individual DNase I cleavage sites using massively parallel sequencing technologies.
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This review describes the salient features of massively parallel sequencing and how it can impact forensic genetics.
