1 Western blot analysis was used to detect the changes in PDX - 1 expression.
2 The PDX model was used successfully to test targeted drugs in vivo.
3 This a-to-β conversion was not caused by activating Pdx 1 in the later glucagon-expressing state.
4 In addition, RNAi technology was used to specifically knock down the endogenous PDX - 1 expression.
5 A specific serum assay for PDX is not commercially available.
6 Conclusions: In LC, islets undergo hypertrophy and exhibit paradoxical expression of insulin and PDX - 1 .
7 This PDX model was generated from a previously untreated HNSCC.
8 This was determined by repeated measures linear regression statistical analysis in four different PDX models.
9 And they are not the first animals to work at PDX , the airport's call letters.
10 We cultured three PDX and three clinical patient specimens with 100% success rate.
11 Methods: A series of truncated PDX - 1 mutants were constructed.
12 PDX studies extend this mechanistic relationship to CCOC tissues.
13 PDXs also varied in their sensitivity to chemotherapeutic agents.
14 Recently, CTCs have been used to generate PDX experimental models of breast and prostate cancer.
15 However, the optimal dose and schedule of LV in PDX treatment has not yet been established.
16 Notably, variable PDX growth rates over time might have implications for the interpretation of translational studies.
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