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Meanings of perpetual vicissitude in English

We have no meanings for "perpetual vicissitude" in our records yet.
Usage of perpetual vicissitude in English
1
After a life of storms and perpetual vicissitude, he died in 1534, aged 48 years.
Lives of the Necromancers
2
It was plain that the nations of Europe were tending to greater depravity, and would be the prey of perpetual vicissitude.
Memoirs of Carwin the Biloquist (A Fragment)
3
His career in America was one of perpetual vicissitudes and full of adventures.
The Story of My Life — Volume 06
4
He knew neither that nor any other art of self-restraint, and, therefore, was in perpetual vicissitudes of riches and penury.
The Wits and Beaux of Society. Volume 1
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