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Activation of the polyol pathway may be responsible for the change.
2
The polyol pathway is a metabolic route able to convert glucose into fructose.
3
The PdCoP catalyst was synthesized via a modified polyol process in teflon-sealed reactor by microwave-heating.
4
Metallic Ru and Rh nanoparticles are synthesized by polyol method, in the presence of a stabilizer.
5
Activation of polyol pathway in HG cells is not responsible for the decrease in intracellular NADPH content.
6
Conclusions: Oxidative and inflammatory stress is the distinct signature that the polyol pathway leaves on retinal vessels.
7
In normal mice, glucose consumption is accompanied by aldose reductase and polyol pathway activation in steatotic areas.
8
These findings have implications for how to evaluate the role of the polyol pathway in diabetic retinopathy.
9
A highly selective nucleophilic substitution reaction, followed by oxidation of the C-Si bond, leads to the desired polyol.
10
High serum glucose concentrations are known to induce the polyol pathway and increase fructose generation in the liver.
11
We surmised that this suppression was due to polyol influx, causing the cells to passively adapt to the stress.
12
Diabetes is associated with activation of the polyol pathway, in which glucose is converted to sorbitol by aldose reductase.
13
Material properties of PPS polymers can be tuned by altering the polyol monomer and reacting stiochiometric ratio of sebacic acid.
14
Cardiovascular impairment may be caused by an increase in polyol pathway flux, by intracellular advanced glycation end-products formation or increased flux through the hexosamine pathway.
15
We have developed a family of synthetic biodegradable polymers that are composed of structural units endogenous to the human metabolism, designated poly(polyol sebacate) (PPS) polymers.
16
It has been proposed that the development of diabetic complications may involve a depletion of cellular myo-inositol due to an increase in polyol (sorbitol) formation.