1
Serrated polyposis syndrome is associated with an increased colorectal cancer risk.
2
Presenting hyperplastic polyposis syndrome is very unusual and may represent a clinical dilemma for correct management.
3
We speculate that BRRS and juvenile polyposis syndrome may have a heterogeneous etiology to cause their syndromes.
4
Germ-line mutations in PTEN have also been described in Cowden disease and in a small number of patients with juvenile polyposis syndrome.
5
Peutz-Jeghers syndrome is a dominantly inherited polyposis syndrome characterized by hamartomatous polyps of the gastrointestinal tract and pigmented lesions of the skin.
6
Through this review, we provide a framework for gastroenterologists to manage the multifaceted nature of pediatric polyposis syndromes.
7
The article provides an overview of hereditary polyposis syndromes of the digestive tract and genetic mechanisms in greater detail.
8
The hamartomatous polyposis syndromes are uncommon but distinctive disorders in which multiple hamartomatous polyps develop at a young age.
9
In this review, we discuss both common and uncommon childhood gastrointestinal polyposis syndromes in terms of clinical presentation, management, and surveillance.
10
Additionally, as many polyposis syndromes are inherited, appropriate genetic testing and management of relatives is vital for the health of the entire family.