Meanings of poorly immunogenic in English

Intestinal and heart transplant model were selected as highly and poorly immunogenic organs.

Subunit vaccines that are poorly immunogenic are often combined with adjuvants for immunization.

All four proteins are poorly immunogenic in mice vaccinated with aluminum hydroxide-absorbed formulations.

This suggests that low mutation burden tumors, which include many pediatric tumors, are poorly immunogenic.

Methods: The poorly immunogenic rat colon carcinoma cells PROb were used in a vaccination assay.

Vaccine administered by ID or IN, although well tolerated, is poorly immunogenic at the doses delivered.

The respective natural antigens are poorly immunogenic ininfected normal mice but elicited antibodies in Lyme disease patients.

The successful induction of T cell-mediated protective immunity against poorly immunogenic malignancies remains a major challenge for cancer immunotherapy.

However, malignant cells are of self origin and only poorly immunogenic, which limits their capability to induce an anticancer immune response.

By optimizing different parameters of the transfection protocol we were able to transform the poorly immunogenic M-3 mouse melanoma cell line into a potent immunogen.

Using an adoptive transfer model we have previously shown that rIL-12 acts directly on DC to enhance presentation of an otherwise poorly immunogenic tumor peptide.

MSCs are poorly immunogenic, and they can modulate immunological responses through interactions with a wide range of innate and adaptive immune cells to reduce inflammation.