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Background: Amyloid deposition is a potential contributor to postoperative cognitive dysfunction.
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Patients undergoing major surgery are at risk for postoperative cognitive dysfunction (POCD).
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Preliminary evidence suggests that postoperative cognitive dysfunction (POCD) is common after lung transplantation.
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Conclusions: In this study, postoperative cognitive dysfunction was not associated with 6-week cortical amyloid deposition.
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Background: Studies on postoperative cognitive dysfunction (POCD) have attracted extensive attention and achieved significant progress.
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Various studies have implicated a potential association between candidate gene polymorphisms and postoperative cognitive dysfunction, yet corroborative studies are lacking.
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We aimed to identify if preoperative frailty or prefrailty is associated with preoperative and postoperative neurocognitive disorders or postoperative cognitive dysfunction.
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Understanding the role of pain signaling after surgery may lead to novel interventions for common complications such as delirium and postoperative cognitive dysfunction.
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We investigated the variants in genes encoding platelet glycoprotein-IIIa and apolipoprotein-E and their relationship with postoperative cognitive dysfunction one year after cardiac surgery.
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Both plasma Abeta(42) and Abeta(40) levels assessed before the surgery were significantly lower in patients who later had postoperative cognitive dysfunction at 3 months.
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Postoperative cognitive dysfunction was determined using Z test scores.
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Methods: The International Study of Postoperative Cognitive Dysfunction recruited patients undergoing noncardiac surgery from 8 countries.
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Postoperative cognitive dysfunction, confusion, and delirium are common after general anesthesia in the elderly, with symptoms persisting for months or years in some patients.