Two patients had subacute stent thrombosis related to premature discontinuation of antithrombotic medications.

Patients also completed a global evaluation of treatment effect at study end or premature discontinuation.

Forty-two percentage of the patients experienced side-effects leading to premature discontinuation in two of 12 patients.

However, the rates of treatment adherence and premature discontinuation of treatment were similar in the two groups.

HPN complications were defined as any cause that led to either premature discontinuation of HPN therapy or catheter replacement.

Thus, clinicians must be cognizant of the phenomenon of scintigraphic flare to avoid premature discontinuation of a potentially beneficial treatment.

Three patients (6%) in the prazosin group experienced symptoms of orthostasis requiring premature discontinuation of the drug and termination from the study.

Adverse effects were common and prevented dose escalation of thalidomide in 75% of patients and led to premature discontinuation of treatment in 35%.

Premature discontinuation of substance use disorder (SUD) treatment is a leading factor associated with poor outcomes.