Meanings of previously unappreciated in English

Further analysis uncovers previously unappreciated transcriptional prepatterning in cortical neural stem cells.

In addition, modern diagnostic techniques often reveal some previously unappreciated abnormalities.

We propose that this is an important and previously unappreciated element of immunosurveillance.

Our data suggest that antagonizing p110δ constitutes a previously unappreciated therapeutic opportunity for diabetic retinopathy.

These findings indicate that targeting EGFR degradation is a previously unappreciated therapeutic option in EGFR-related NSCLC.

Altogether, these data indicate a previously unappreciated functional diversity and complexity within the vertebrate pard6 gene family.

Our study demonstrates that Entpd5 represents a previously unappreciated essential player in phosphate homeostasis and skeletal mineralization.

Overall, our results reveal a previously unappreciated mechanism for inherited MPN risk through the modulation of HSC function.

Our work suggests that human Mdm1 homologues may play previously unappreciated roles in interorganelle communication and lipid metabolism.

Here we delineate a previously unappreciated role for CAFs as determinants of the molecular subtype of breast cancer.

Combined, these results uncover a previously unappreciated role for acute posttranslational palmitoylation at defined circuit components to regulate learning.

The discovery of enzymes responsible for previously unappreciated microbial metabolic pathways furthers our understanding of host-microbe and microbe-microbe interactions.

Although other forkhead transcription factors have been implicated in immunity, a role for FoxK in antiviral defense was previously unappreciated.

These challenges have accentuated the need for receptor tools that allosterically stabilize and regulate receptor function through unique, previously unappreciated mechanisms.

This interaction appears to augment dendritic-cell-induced T cell activation and identifies a previously unappreciated pathway in the regulation of type-2 immunity.

We show that most single antiretroviral drugs show previously unappreciated complex nonlinear pharmacodynamics that determine their inhibitory potential at clinical concentrations.