Meanings of proinflammatory mediators in English

Although influenced by multiple proinflammatory mediators, identification of suitable therapeutic candidates remains elusive.

Elevated levels of proinflammatory mediators cause both local and systemic effects.

In clinical trials, inhibition of proinflammatory mediators has not proven effective.

These changes concentrate proinflammatory mediators, reduce mucociliary clearance of bacteria and subsequently activate cellular signaling.

We compared the effect of rhDNase and HS on cationic proinflammatory mediators in CF sputum.

This risk has been attributed to visceral adipose tissue (vAT) expansion associated with increased proinflammatory mediators.

The signal transduction pathways regulating smooth-muscle gene expression and production of cytokines in response to proinflammatory mediators are undefined.

We hypothesize that increased A(2B)R signaling in diabetes increases insulin resistance in part by elevating proinflammatory mediators.

Recent studies have shown that administration of proinflammatory mediators increases alcohol consumption, while anti-inflammatory drugs, such as minocycline, decrease consumption.

Diabetes resulted in widespread expression of RAGE, followed by expression of proinflammatory mediators, without major alterations in oral microbial profile.

Severe sepsis, septic shock, and related inflammatory syndromes are driven by the aberrant expression of proinflammatory mediators by immune cells.

These data suggest that estrogen suppresses lung inflammatory responses in mice through an effect on vascular cell adhesion molecules and proinflammatory mediators.

The result also altered the distorted level of proinflammatory mediators and inflammatory mediator, which further reinforce the implication of MM in CFA induced arthritis.

Global gene expression analysis indicated that the luMSCs are a unique stromal population differing from lung fibroblasts in terms of proinflammatory mediators and profibrotic pathways.

Previously, we showed that the presence of CLS-B is associated with elevated tissue levels of proinflammatory mediators and aromatase, the rate-limiting enzyme for estrogen biosynthesis.

Proinflammatory mediators involve the development and progression of heart failure.