Meanings of proteolytic cleavage in English

Interaction between two membrane proteins is detected by proteolytic cleavage of a protein fusion.

Subsequent proteolytic cleavage of Gag triggers rearrangement of the particles to form mature infectious virions.

A number of advanced studies have been published aiming at deciphering the mechanisms of proteolytic cleavage.

The roles of proteolytic cleavage have been intensively investigated and discussed during the past two decades.

Caspases are synthesized as inactive zymogens and are generally activated by proteolytic cleavage to form the catalytically active enzyme.

Following proteolytic cleavage of combined labeled proteins, peptides were fractionated by multidimensional chromatography and subsequently analyzed via automated tandem mass spectrometry.

Metal binding to APP or its fragments affects its structure and its proteolytic cleavage and therefore its physiological function at the synapse.

The smaller isoform is identical in molecular weight to the protein expected from proteolytic cleavage of full-length Nef-2-HOM by the virion-based protease.

The discovery that Notch activation involves a proteolytic cleavage to release the intracellular domain (NICD) revolutionized the field of Notch signaling.

The current study has shown for the first time that elevated sIL-6R after HIIT exercise is derived from both proteolytic cleavage and differential splicing.

The latter event was associated with a proteolytic cleavage of Beclin-1, leading to the accumulation of a 50-kDa fragment.

Both CD40 and CD40 L have a membrane form and a soluble form generated by proteolytic cleavage or alternative splicing.

This defect was due to a rapid proteolytic cleavage of GPVI, as shown by the release of the 55 kDa extracellular domain into the supernatant.

Decreased serum C-FGF23 levels were found in βTh patients which may be attributed to inhibition of proteolytic cleavage of iFGF23.

Caspase activation and proteolytic cleavages are the major events in the early stage of apoptosis.

The latter membrane fusion requires an S protein conformational flexibility that is facilitated by proteolytic cleavages.