Meanings of proximal promoter in English

The proximal promoter of lck directs gene expression exclusively in T cells.

Multiple putative GATA elements were identified in the Tie1 proximal promoter.

Of these, using the EZ-Retrieve web service, proximal promoter sequences were available for 33 genes.

These HSs are located in the proximal promoter and in the first intron of the gene.

Moreover, the proximal promoter is not a major driver of circulating soluble ST2 under the conditions tested.

Analysis of the proximal promoter of the insulin-like growth factor I receptor revealed a novel AP-2-binding site.

An extended LMO2 proximal promoter fragment displayed strong endothelial activity, while the distal promoter showed weak forebrain activity.

The TATA-less proximal promoter contains multiple Sp1 binding sites and a consensus sequence for sterol regulatory element binding protein.

On either side of the proximal promoter region, two negative regulatory domains might reduce BACE2 expression under an induced condition.

Although each of the transcription factors bound to the StAR proximal promoter, we observed cell-specific binding patterns for individual factors.

We have delineated the proximal promoter element responsible for cell cycle-dependent transcription of a human histone H4 gene in vivo.

Our results show that the SP-10 proximal promoter, which activates transcription in spermatids, functions as an insulator in somatic cells.

Five polymorphisms identified between the iP and iNP in the proximal promoter region did not influence differential expression between the strains.

IL-1β decreased NOX-4 expression through a transcriptional mechanism that involved response elements situated in the proximal promoter.

Reporter and chromatin immunoprecipitation assays demonstrated a direct, functional interaction by AP-2gamma at the CDKN1A proximal promoter.

Previous studies had established that the cis-regulatory targets of PUFA control were located within the proximal promoter region of the S14 gene, i.e.