Meanings of putative binding in English

Within its 5' flanking sequence, the putative binding sites of several transcriptional regulatory factors existed.

Residues in the putative binding trench likely to be involved in fibrinogen binding were identified.

The SNPs located in the gene promoter modify the putative binding sites for various trans-acting factors.

Their putative binding modes were investigated by correlating their biological data with features of the pharmacophore model.

The TSG-6 Link module was shown to interact with hyaluronan, and a putative binding surface was identified on the structure.

Moreover, mutation of the putative binding site reduced Sp3 binding in EMSAs and increased promoter activity in luciferase reporter gene assays.

In silico docking was performed to identify putative binding sites in CRMP-2 that may modulate the effects of LCM on VGSCs.

The putative binding model and mutagenesis studies provide a novel substrate recognition mode explaining the polymannuronate specificity of PL-14 alginate lyases.

The CoMFA models were found to be more detailed in the putative binding site by exploring multiple conformations of each ligand.

The phosphoinositide-PH domain interaction can be abolished selectively by point mutations in the putative binding pocket predicted by molecular modelling and NMR spectroscopy.

The putative binding surface of CedA is predominantly positively charged with a number of basic residues surrounding a groove largely dominated by aromatic residues.

Furthermore, we obtained human Snail promoter sequence from TRED-Promoter Database and identified a putative binding site of NF-kB in the sequence through TFSEARCH analysis.

In silico analysis indicated the presence of putative binding sites for all five transcription factors in the promoter region of many Sult and PAPSs isoforms.

The approach developed focused on mapping clusters rich in overlapping predicted epitopes, and ranking these "hotspot" regions according to the density of putative binding epitopes.

As a result 1838 pSNPs were detected, 75% of which modify (by either gain or loss) putative binding sites of known transcription factors.

Putative binding sites for EmrR and AcrR were suggested.