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1 Our results have identified 414 protein targets for modification by reactive aldehydes in ALD.
2 Early B cells from these mice exhibit excess reactive oxygen species and reduced metabolism of reactive aldehydes .
3 Cardiac ischemia and reperfusion promote oxidative stress, leading to the accumulation of reactive aldehydes that cause cardiac damage.
4 Mitochondrial aldehyde dehydrogenase 2 is emerging as a key cardioprotective enzyme for its central role in the detoxification of reactive aldehydes .
5 The production of reactive aldehydes such as 4-hydroxynonenal (4-HNE) is proposed to be an important factor in the etiology of alcoholic liver disease.
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