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1 DNA-bound PRs regulate transcription via interaction with other nuclear proteins and transcription factors.
2 Although presumed to regulate transcription , its target genes are largely unknown.
3 The activated MAPK can translocate to the nucleus where it can regulate transcription factors.
4 Calcium-binding proteins regulate transcription and secretion of pancreatic islet hormones.
5 To regulate transcription , AR recruits a series of coactivators that modify chromatin and facilitate transcription.
6 These results suggest that bFGF can regulate transcription directly in the nucleus in a gene-specific manner.
7 HDAC inhibitors might also regulate transcription elongation and have been shown to impinge on alternative splicing.
8 We have isolated and characterized two interesting steroid receptor-interacting proteins that regulate transcription in opposite directions.
9 Moreover, they regulate transcription factors such as signal transducer and activator of transcription and nuclear factor kB.
10 The molecules that regulate transcription often are major drug targets, for example in the fight against cancer.
11 MafB appears to directly regulate transcription of these genes, because binding was observed within endogenous control region sequences.
12 Both adaptation and maladaptation are the results of metabolic signals that regulate transcription of key cardiac regulatory genes.
13 We speculate that Cut functions in conjunction with these factors to regulate transcription of as yet unidentified targets.
14 Although the qualitative aspects by which individual receptors regulate transcription are well understood, a quantitative perspective is less clear.
15 Once in the nucleus Smad proteins interact with other DNA binding proteins to regulate transcription of specific target genes.
16 This specificity appears to involve cis-regulatory elements, some of which also regulate transcription of the germline antigen receptor loci.
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