Meanings of requires substantial in English

However, furthering this goal requires substantial infrastructural and cultural change.

Nor will I rush a mission that requires substantial preparation.

Continuous flow peritoneal dialysis requires substantial technical improvements before this technique can be widely accepted.

DNA fingerprinting of Mycobacterium tuberculosis by IS6110 restriction fragment length polymorphism analysis requires substantial high-quality DNA.

Therefore, the most ambitious task is determining the quality of the bone material, which requires substantial experience.

Analysts say it requires substantial investment in its research and development capacity to boost internal expertise by then.

It is a multijoint action that requires substantial muscular effort from primarily the ankle, knee, and hip joints.

It requires substantial involvement of relevant stakeholders to address determinants of the studied behaviour and to facilitate empowerment.

The real hero requires substantial filling.

Effective management of chronic diseases involves sustained changes in health behavior, which often requires substantial effort and patient burden.

There are plenty of failed banks still to sort out and the process of bank supervision requires substantial redesign.

Successfully performing CT angiography in these children requires substantial communication and coordination between the radiologists and clinical care providers.

Background: The preparation of a randomized controlled trial (RCT) requires substantial resources and the administrative processes can be burdensome.

Analysis of RNA modifications by traditional physico-chemical approaches is labor intensive, requires substantial amounts of input material and only allows site-by-site measurements.

It requires substantial need for enforceable regulations, comprehensive industry controls, economic feasibility plans, and the latest ultra-expensive technology such as plasma gasification plants.

It requires substantial and thorough treatment as much as rheumatism, dyspepsia, or any other of the numerous diseases to which humanity is subject.