Meanings of resistant phenotype in English

Hypoxia contributes to the aggressive and treatment- resistant phenotype of pancreatic ductal adenocarcinoma.

However, a drug resistant phenotype gradually arises after repeated doses of chemotherapeutic NP.

Recent research suggests that another family member ErbB3 abets emergence of the castration- resistant phenotype.

The resistant phenotype was associated with the emergence of mutations in the gp120 molecule.

This multi-drug resistant phenotype that challenges health care workers worldwide is caused by an array of resistance determinants.

The emergence of mutations in the envelope gp120 of the resistant virus paralleled the emergence of the resistant phenotype.

Tumors with typical multidrug- resistant phenotype were excluded because MEN 10755 was found unable to overcome resistance mediated by transport systems.

Here, we demonstrate that marmosets exhibit two phenotypes upon infection with GBV-B: the susceptible phenotype and the partially resistant phenotype.

Such an intermediate- resistant phenotype could increase a cell population under CIP-selective pressure and might promote the emergence of highly resistant isolates.

Various inhibitors have been tested for their ability to revert the CPT- resistant phenotype to specifically understand the inhibition of LdABCG6 transporter.

Many strategies used to kill cancer cells induce stress-responses that activate survival pathways to promote emergence of a treatment resistant phenotype.

In this study, we investigated whether the human Fas receptor itself, or the Fas transduction pathway was responsible for the resistant phenotype.

Introduction of these mutations into an infectious molecular clone identified all changes to be required for the fully AZT- resistant phenotype of SFVmac.

The maintenance of the resistant phenotype of the clones requires the serial subcultivation of the cells in the presence of activated EGSV.

It is likely that this hormone- resistant phenotype is a result of alteration of GR function but not of GR expression or gene structure.

Moreover, the glucocorticoid- resistant phenotype was stable in culture and did not revert after treatment with 5-azacytidine or upon stable expression of GR cDNA.