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1
The pRb inhibits transcription of genes involved in growth control (
reviewed
in
ref
.
2
In mammals, dosage compensation of X-linked genes is achieved by the transcriptional silencing of one X chromosome in the female (
reviewed
in
ref
.
3
Insulin is a polypeptide hormone of major physiological importance in the regulation of fuel homeostasis in animals (
reviewed
in
refs
1,2).
4
This effect may be the basis of the pertussis-toxin-sensitive phospholipase C activation seen in some cell systems (
reviewed
in
refs
13 and 14).