Meanings of robust optimization in English

Conclusions: IMPT's sensitivity to uncertainties can be improved by using robust optimization.

Mitigation of range and setup uncertainties through robust optimization is discussed.

The robust optimization took setup and range uncertainties into account.

The HimpsPT plans were more robust than the clinical IMPT plans generated without robust optimization.

We have developed a robust optimization approach for intensity modulated proton therapy treatment plans with multi-isocenter large fields.

Intensity modulated ion therapy robust optimization was performed by a quasi-Newton iterative method based on dose-volume objective function.

Dose contributions for a number of range and setup uncertainties were calculated, and a worst-case robust optimization was performed.

Methods: We analyzed the nominal and worst-case robust optimization IMPT plans of seven patients with head and neck cancer patients.

MC based radiobiological and robust optimization was made flexible to incorporate dose-volume histogram constraints and to be independent of RBE models.

They also compared conventional and robust optimization of IMPT-DET with three-dimensional IMPT (IMPT-3D) to gain understanding about how plan robustness is achieved.