From this study, the first class of dual nNOS- selective inhibitors was identified.

Steroid hormones and glucocorticoids have been characterized as selective inhibitors of lymphopoiesis.

Additional articles discuss current approaches to identify selective inhibitors of the AKT pathway.

HDAC8 active site unique features facilitate the design of selective inhibitors.

All three are potent, selective inhibitors of influenza virus A and B sialidase.

These results suggest that HDAC3- selective inhibitors may be effective in preventing cytokine-induced beta-cell apoptosis.

The general problem of developing selective inhibitors is discussed.

Cyclo-oxygenase-2 selective inhibitors are frequently used to manage osteoarthritis.

Potent and selective inhibitors of tankyrases have recently been characterized to bind to an induced pocket.

The contribution of individual activation pathways to different biological processes can be assessed by using pathway- selective inhibitors.

A novel class of potent and selective inhibitors of KDR incorporating an indazole moiety 1 is reported.

Although many such inhibitors have been designed and synthesized, but selective inhibitors for HDAC isoforms are lacking.

These results suggest that thiadiazole urea heterocycles which incorporate a substituted phenylalanine can provide selective inhibitors of stromelysin.

Analysis of the electron density distribution showed that more effective binding with COX-2 receptor was observed for selective inhibitors.

Moreover, inhibition of these pathways using selective inhibitors could significantly reduce the cytokine and chemokine secretion induced by PspA.

Potent and selective inhibitors of this enzyme have been identified and shown to inhibit HCV replication in tissue culture.