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Meanings of significant responsibility in English

We have no meanings for "significant responsibility" in our records yet.
Usage of significant responsibility in English
1
L.A.'s no place for the weak-minded and being Punk carries a significant responsibility.
Freaks and revelations
2
It becomes possible to influence how people think about a given question and with that comes significant responsibility.
The Irish Times
3
The drinks industry (both publicans and producers) has to take a significant responsibility for this state of affairs.
The Irish Times
4
The reports also singled out Barry Zubrow, the bank's former chief risk officer, who was also singled out for " significant responsibility for failures."
The Guardian
5
In many cases, trustees are lay people who have significant responsibilities placed on them.
The Irish Times
6
He had practised great self-repression; he had accepted his future life suddenly, but with all its significant responsibilities.
A Son of the Hills
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