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A biopsy of the skinnodule was performed which showed infiltration of lymphoid blast cells which were CD30 positive.
2
The second patient presented with a skinnodule that spontaneously resolved without therapy, and subsequently recurred in tongue and skin a few years later.
3
Six months after finishing the therapy, multiple skinnodules appeared on her abdomen and chest wall.
4
Subsequent skinnodules of the right thigh occurred over the next 12 months, associated with recurrent lymphedema of the leg.