Meanings of specific substrate in English

Here we provide evidence that CD43 regulates tyrosine phosphorylation of a specific substrate in T cells.

Moreover, this enzyme was capable of oxidation of syringaldazine, which is a specific substrate for laccase.

TRIM proteins rely upon the correct placement of an N-terminal RING domain, with respect to C-terminal, specific substrate-binding domains.

Recent investigations have demonstrated the efficacy of chemical genetics using ATP analogues and modified protein kinases for specific substrate labelling.

Blocking Mrp activity by MK-571 resulted in accumulation of the Mrp specific substrate carboxyfluorescein in RLF phi 13 cells.

This study is the first to identify a novel PKD- specific substrate, DLP1 in mitochondria, as well as the functional role of PKD in cardiac mitochondria.

A fluorimetric assay was applied using the PLA2 specific substrate NBDC6-HPC, thin-layer chromatography of reaction products, and digital image scanning for signal detection.

In order to distinguish between different types of enzymes, specific substrates are needed.

In fast twitch muscle, no specific substrates of CaMKII have yet been identified in nonjunctional SR.

Akt1 is critical for many in vivo functions; however, the cell- specific substrates responsible remain to be defined.

Gingipain activity was detected using synthetic- specific substrates.

Therefore, to target specific substrates, many phosphatases associate with distinct regulatory subunits and thereby modulate multiple cellular processes.

Moreover, CatB enzymatic activity examination showed the nuclear CatB exhibited the proteolytic activity to cleave its specific substrates.

The purified protein catalyzed the oxidative deamination of L-amino acids, and the most specific substrates were L-Tyr and L-Phe.

The key to better understanding the mechanisms that control this process is to identify the specific substrates that each protease targets.

SNARE proteins are specific substrates of botulinum neurotoxins (BoNT) which are now widely used for therapeutic and cosmetic purposes.