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Haspin inhibitors did not block Aurora B localization to the spindlemidzone in anaphase or Aurora B function in cytokinesis.
2
Error-free cell division depends on the assembly of the spindlemidzone, a specialized array of overlapping microtubules that emerges between segregating chromosomes during anaphase.
3
Spindle checkpoint proteins accumulate mainly within the spindlemidzone and inhibit anaphase onset.